CryoPen Cryotherapy

with No Comments

Now at Vanité Clinic, CryoPen uses cryotherapy to remove skin tags, warts, verrucas and other skin lesions. Cryotherapy is a procedure that uses extreme cold to destroy tissue. The process is called cryo-necrosis, tissue destruction by freezing.

How is cryosurgery better than other methods of removing skin lesions?

Cryotherapy requires no anaesthesia and has less scarring than other techniques of skin removal with minimal post-op care. Treatment goes fast and can be integrated into daily practice.


Prices start from £40 per treatment



Treatment Video


How does CryoPen treatment work?

The applicator is held as close as possible to the skin imperfection and moved quickly toward and away from it. This could be from 1-30 seconds, depending on the size and depth. After the first freeze cycle, the tissue can thaw for about 30 seconds. Now the second freeze cycle will begin. The tissue will freeze faster during the first freezing cycle.

Can anyone have cryotherapy?

Yes, but cautions about skin type and location be considered prior to deciding on freeze times. People with high levels of cryoglobulins should be treated with caution. If with dark skin, one may not want to have cryotherapy, it will kill the melanocytes around the treated area, making the skin in that area lighter.

How long will results last?

For most lesions, cryotherapy is a permanent removal. Some lesions are harder to remove than others. In addition it is necessary to obtain a result with the least damage to the surrounding skin. In other instances, a deep lesion may take several aggressive treatments to get results. It is important to have an instrument that can adapt to variable dosing of power.

Will there be any scarring after the CryoPen treatments?

This does normally occur. Darkening or lightening of the skin may occur temporarily. Both generally last for a few months. The pigment change is more common in darker skin types.

How many treatments will I require?

Most small common warts will respond to a single treatment. However, certain types ad very deep ones can be very difficult to remove and may require more than one treatment.

What activities be limited after CryoPen treatments?

There are no limitations on activity except to protect the area from damage or abrasion. Swimming and showering is not a problem.

What type of skin conditions can be treated using the CryoPen?

  • Skin
  • Skin tags
  • Age spots
  • Warts
  • Actinic Keratosis
  • Verruca’s
  • Milia
  • Cherry angiomas
  • Benign skin imperfections


Prices start from £40 per treatment



How does CryoPen work?

CryoPen™ is a state of the art treatment that uses extreme cold, or cryotherapy, to painlessly and safely destroy unwanted, benign and superficial lesions on the surface of the skin, such as warts, skin tags, verrucae, milia, cherry angiomas, scars, and resistant hyperpigmentation.

It has four main benefits over other treatments:
– CryoPen therapy takes far less time; with treatment sessions lasting less than 2 minutes.
​​- No anesthesia is required and it is virtually painless
​​- It is one of the least invasive lesion treatments in the market
​​- It is used in the treatment of virtually any benign skin lesion

Skin Concerns Treated
Skin lesions, Pigmentation on both face and body.

How safe is cryotherapy with CryoPen?

Cryotherapy is a low-risk procedure. CryoPen™ delivers N2O directly to the area, and not the healthy surrounding tissue. CryoPen™ is both CE and FDA registered.

Does it hurt?
It is virtually painless. The accuracy of CryoPen™ means that healthy skin around the site of the lesion is less likely to be effected, and therefore it is not painful.

Treatment is generally very well tolerated, even with those with a low pain threshold. The sensation is similar to a stinging nettle on the skin when the nitrous oxide reaches the bottom of the area, but this vanishes quickly.

There might be a little residual stinging for a few minutes after treatment. The area will be slightly itchy for about ten minutes. Occasionally a blister might form and persist for a few hours. This is NOT to be confused with traditional Cryotherapy, which can be very painful as it usually hits healthy tissue.

Will it leave a scar?
Generally, no. Cryosurgery with CryoPen™ preserves the tissue matrix which is relatively cold resistant, and therefore allows for proper cosmetic healing with minimal scarring. This will of course depend on your skin type, and how well you follow the aftercare advice. Hypo-pigmentation in the area (a small pink patch of skin, where new skin has formed, that is lighter in colour) may be visible for 2-6 months. This color loss may take longer to return in darker pigmented skin.

Solar Lentigo, Sun Spots and Pigmentation

To protect itself from the damaging effects of the sun, your skin increases its production of the dark brown pigment called melanin. The extra melanin makes your skin look darker or sun-tanned. In some cases, the sun causes an uneven increase in melanin production, which produces irregular colouring or pigmentation of the skin.

Lentigo or lentigines may evolve slowly over years, or they may appear suddenly. They may occur anywhere on the body and vary in colour from tan-brown to black.

They may require a few treatments with CryoPen. The area will go darker after treatment, and flake/slough away to reveal new skin.


Skin Tags (Fibroepithelial polyp/papilloma)

Skin Tags are a common fibrous skin condition found in areas of friction such as the armpits, under the breasts, groin or around the neck where necklaces or collars may irritate. They often present with a neck like a mushroom and vary in size from a tiny speck, smaller than a grain of uncooked rice, to the size of a large pea or larger. They are viral in nature (Human Papilloma Virus HPV) and whilst not infectious they can proliferate on individuals with some people suffering from hundreds of them.

CryoPen works like advanced electrolysis but using a freezing technique instaed of heat. it is a quick, easy way of removing skin tages of all sizes, in a safe and effective manner.

There are two different methods of skin tag removal for different types of tags:

1) Small skin tags with no neck: The fine jet of nitrous oxide is applied to the skin tag, this freezes and falls off over the next couple of days.

2) Larger skin tags with a neck: The skin tag is lifted with tweezers and the neck of the tag is frozen, the tag then falls off in a couple of days.


Small Blood Spots (Campbell de Morgan Spots or Cherry Angioma)

They present themselves as slightly raised or dome shaped red spots and are of unknown origin. They are mostly seen on the trunk in middle aged and elderly clients and are even more common in men than women. Larger ones (50p size+) will need more than one treatment. Smaller ones often disappear at time of treatment.

CryoPen is used to freeze the blood spot, smaller ones going instantly, larger ones taking a couple of sessions.



Millia are small white lumps lying superficially under the surface of the skin. They are a retention of keratin and sebaceous material within the pilosebaceous duct, eccrine sweat duct, or the sebaceous collar surrounding vellus hair. Their exact cause is unknown although they are often related to diet with a high cholesterol count, excessive Vitamin C, too rich moisturising cream and are also associated with dry skin which can be acidic.

They can all be treated easily with CryoPen freezing the lump, drying it up so that the hard keratinised centre is broken down and this will then be absorbed by the skin following treatment. This is a much gentler way to treat them, as opposed to removing them with a microlance, which can damage the skin.

Dermatosis Papulosa Nigra

Small to medium, raised benign skin lesion which varies in colour from brown to black. They are usually found on the face, in particular around the eye area, and tend to be more common on dark-skinned individuals.

The cause is unknown, but generally appear after puberty, and grow in size and number with age. They can be hereditary.

The skin lesion is frozen and falls off after a couple of days. The skin can be a bit lighter in colour straight after and then this evens out, sometimes going slightly darker than the surrounding skin.

Seborrhoeic Keratosis

Seborrhoeic keratosis is a benign, asymptomatic mass, primarily caused by the ageing process. It is also known as seborrhoeic warts, senile warts, barnacles or basal cell papilloma. They have a thick wart-like surface and are usually colourless when they appear and become brown to black over time. Seborrhoeic keratosis can be confused with other skin conditions, so it is advisable to seek a GP’s advice before visiting.

Freezing the mass kills the surface skin cells, this scabs and falls off and a new smoother skin is relieved underneath. This may take a few session to get the smoothest results and they can grow back and need follow on top up treatments.


Warts & Verruca's

Warts usually have a “cauliflower” like appearance, and commonly appear on the hands. Verruca’s sometimes called plantar warts or spelled verrucae – are warts that develop on the soles of the feet. CryoPen is great at treating stubborn warts and verruca’s, even if other methods have failed. They can turn dark and flake away after treatment.

Viral lesions are more difficult to treat being the lesion and the virus needs to be dealt with. Multiple treatments will be needed depending on the size and the depth. We may ask you to exfoliate any dry or hard skin from the wart/verruca before your appointment.


CryoPen is perfect for mole removal. But, you will need to check with your GP prior to treatment if you wish for us to remove a mole.

Moles turn darker after treatment, flaking away to reveal new skin. Depending on the size and the depth, sometimes a second treatment is required if they’re still apparent after 4 weeks.

Contraindications & After Care


Unfortunately not all treatments are for everyone. Please check our contraindications list to make sure you avoid disappointment.

– Impaired sensation or circulation
– Open wound (treatment area)
– Skin Cancer (treatment area)
– Hypersensitivity to cold
– Recent scar tissue (treatment area)
– Raynaud disease (for digit cryotherapy)
– Prone to Keloid Scarring


Side Effects: CryoPen Therapy is relatively low risk and side effects and complications are usually minimal. Some side effects may occur as a result of the treatment. These may include:

Headaches: Not uncommon when freezing on the forehead, scalp and temples. Can last for 2 hours.

Pigment Changes: Both hypo (lightening of the skin and hyper (darkening of the skin) pigmentation. Can last a few months or longer.

Nerve Damage: Although rare, damage to nerves is possible especially where the nerves are close to the skin surface (fingers, wrist, behind the ear). Reports suggest that symptoms disappear after several months.

Blisters: These may appear on the treated area but usually disappear after a few hours.

Shards of Ice: The CryoPen delivers a high pressure jet of nitrous oxide. This jet can cause shards of ice to be thrown into the air to a distance of up to 30cm. They will thaw quickly and will not damage healthy skin.

Damage to hair follicles: Hair follicles are easily damaged by cryosurgery and permanent alopecia to the treated area is not uncommon.

Specific pre-treatment information for verrucae and warts:

In the days leading up to your appointment, it is a good idea to give a wart or verrucae a bit of TLC!

The treatment works best when the skin covering these lesions is soft and slightly opened. Follow the steps below to allow the treatment to work effectively:

Soak the lesion in a bowl of warm, soapy water for 20 minutes

With a pumice stone or emery board (nail file), gently scrub the lesion until the skin becomes rough.

Please do not scrub so hard that you make the area sore. Discontinue these steps if bleeding occurs. You are not trying to open a wound or cause discomfort. However, the more deeply the jet of nitrous oxide can penetrate, the better the chances of removal after one treatment are.

If you’re ready to go ahead and book your treatment, please contact Vanité Clinic to discuss a suitable appointment date.

Post Treatment Information

If you have had a treatment to remove a skin lesion, you might like to know what to expect in the coming days. While there is very little aftercare required, there are a few things you should be aware of.

Blisters: Blistering can happen with any cryotherapy treatment and is indiscriminate.

The CryoPen is the most effective way of avoiding blisters as we are only treating the affected area and not healthy tissue. If a blister does appear, please don’t pop it. It will go down on its own. If it pops, weeping may occur. If so use a smear of Savlon or Germolene cream twice a day. An adhesive dressing such as a plaster can be used to cover the area to protect it.

Skin Tags: These turn black at the base and drop off over a period of one to six weeks. Larger skin tags of 3mm+ may need a second freeze. Please contact us after six weeks if they need to be retreated. If the area does become tender you can use use Savlon or Germolene twice a day. A plaster can be used to cover the area to stop the treated area being irritated by clothing rubbing on it.

Warts and Verrucae: It is recommended if they are still there, warts and verrucae should be re-treated 4 weeks after your first treatment. There is no aftercare apart from if the treated area develops a blister.

Milia: These are superficial keratin filled epidermal cysts and normally flatten and disappear with Cryotherapy quite quickly. There is no need to do anything other than follow the blister advice if one appears

Pigmentation and cherry Angiomas: The treated area may raise and look like a bee-sting. Do not worry this is perfectly normal. The redness will subside in a few hours.

General advice for all skin lesions

In the case of all lesions, over the next 24 hours the area will go darker and develop a crust on the surface. Do not pick this off. When it naturally falls away you will see new skin which is a shiny pink colour. This is not scarring. It will re pigment over the following weeks and could take several months.

The histamine in the area which was treated will create an itchy sensation for between ten and sixty minutes, do not worry this is perfectly normal.

Do not pick the treated area at any time after treatment otherwise the area will take longer to heal. If a wheel/scab is knocked off accidentally it will also take longer to heal, but you should still have the same outcome of a successful treatment.

Please use a sunblock factor 50 on any pigmentation removal until it has re-pigmented, this may take up to eight weeks.

You can continue to use make up, deodorant or perfumes on treated areas but try and leave for as long as you can on the day of treatment.

If the small crust has not fallen off after four weeks please wait until it has done so before contacting the clinic. Skin sometimes takes several weeks and even months to regenerate.

If the skin being treated is tanned please remember the healing skin will no longer be tanned. It will eventually re-pigment as it matures.

Permanent alopecia can occur in a treated area which is usually covered with hair.
Treatments that do not heal after six weeks should be reviewed by your doctor or dermatologist. Please contact us to tell us if this happens.


Find out more

For more information or to book a consultation…